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Sermorelin
Sermorelin is a synthetic peptide studied for its ability to naturally stimulate the body’s own growth hormone production by mimicking the action of GHRH, especially in age-related GH decline.
Quantity: 1
All peptides arrive in powdered form for stability.
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Each batch is tested and certified to meet or exceed 99% purity standards.
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Double-tested to ensure the highest quality for the most effective research.
What is Sermorelin?
Sermorelin is a synthetic analog of Growth Hormone-Releasing Hormone (GHRH 1-29), designed to stimulate the pituitary gland to produce and release endogenous growth hormone (GH). While it has a shorter half-life compared to peptides like CJC-1295, Sermorelin has been widely studied and used for its anti-aging, recovery, and metabolic benefits. It was originally FDA-approved for treating growth hormone deficiency in children.
Potential Benefits Shown in Studies
- Increasing natural growth hormone and IGF-1 levels
- Supporting lean muscle mass and fat loss
- Enhancing recovery, strength, and endurance
- Improving sleep quality and tissue repair
- Promoting youthful skin, hair, and joint health
- Supporting bone density and anti-aging effects
- Boosting energy and overall wellness
Mechanisms of Action
Sermorelin works by:
- Mimicking natural GHRH, binding to pituitary receptors
- Triggering pulsatile GH release, preserving physiologic rhythms
- Increasing IGF-1 levels, promoting muscle repair and cellular regeneration
- Avoiding GH oversaturation, allowing better feedback regulation
- Enhancing fat metabolism and tissue healing via GH/IGF-1 axis
Its action is more natural and self-limiting than exogenous growth hormone, making it ideal for long-term optimization strategies.
Molecular Structure of Sermorelin
Sequence
Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gly
Molecular Properties
Sermorelin Research Highlights
Sermorelin, a synthetic analog of GHRH (1–29), stimulates the pituitary gland to secrete growth hormone in natural, pulsatile patterns, maintaining feedback control and minimizing desensitization.
Source: pep-pedia
Originally approved in 1997 for treating childhood growth hormone deficiency, Sermorelin showed efficacy in reversing pediatric growth failure without the constant hormonal exposure of direct GH therapy.
Source: Wikipedia
