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DISCLAIMER: This product is strictly for research use only. It is meant solely for laboratory testing and in vitro studies-not for use in or on humans or animals. All details provided on this site are for educational purposes. This item is not intended to be used as a drug, supplement, or cosmetic, and must not be misrepresented as such.

CJC-1295 (No DAC)

CJC-1295 (No DAC)

CJC-1295 (without DAC) is a synthetic peptide designed to mimic Growth Hormone-Releasing Hormone (GHRH), stimulating the pituitary gland to naturally produce and release growth hormone (GH). Unlike the DAC version, CJC-1295 (No DAC) has a shorter half-life, making it better suited for more controlled and pulsatile GH release—closer to the body's natural rhythm.

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All peptides arrive in powdered form for stability.

Third-Party Verified Purity
Third-Party Verified Purity

Each batch is tested and certified to meet or exceed 99% purity standards.

Made in the USA
Made in the USA

Produced in United States WHO/GMP and ISO 9001:2015 certified facilities.

Rigorous Quality Control
Rigorous Quality Control

Double-tested to ensure the highest quality for the most effective research.

What is CJC-1295 (No DAC)?

CJC-1295 (No DAC) is a synthetic peptide that mimics Growth Hormone-Releasing Hormone (GHRH 1-29), designed to stimulate pulsatile release of natural growth hormone (GH). Unlike its DAC-modified counterpart, this version of CJC-1295 has a shorter half-life (~30 minutes), producing more physiologic GH pulses without prolonged systemic elevation. It is often studied for its effects on recovery, muscle repair, fat metabolism, and anti-aging support.

Potential Benefits Shown in Studies

  • Boosting natural growth hormone and IGF-1 levels
  • Supporting lean muscle growth and recovery
  • Reducing body fat through enhanced metabolism
  • Improving sleep quality and tissue regeneration
  • Promoting anti-aging effects on skin and joints
  • Enhancing energy, strength, and endurance
  • Supporting cellular repair and immune function

Mechanisms of Action

CJC-1295 (No DAC) operates by:

  • Binding to GHRH receptors in the pituitary gland
  • Stimulating natural GH release in pulses, mimicking physiologic secretion
  • Elevating IGF-1 levels, which mediate many of GH's anabolic effects
  • Avoiding desensitization due to its shorter active window
  • Reducing fat mass and supporting lean tissue repair

This version is often used in combination with Ipamorelin to amplify GH release while preserving the body's natural rhythms.

Molecular Structure of CJC-1295 (No DAC)

CJC-1295 (No DAC) molecular structure

Sequence

Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser

Molecular Properties

Formula

C₁₅₂H₂₅₂N₄₄O₄₂

Weight

3367.88 g/mol

Source
PubChem

CJC-1295 (No DAC) Research Highlights

CJC‑1295 without DAC is a short-acting analog of GHRH that reproduces the body’s natural growth hormone (GH) pulse patterns, with a half-life of around 30 minutes.

Source: pep-pedia

Its short duration allows for frequent administration that avoids pituitary down-regulation—a key advantage for maintaining physiologic GH sensitivity.

Source: hkroids

Used in conjunction with GHRP peptides like Ipamorelin, CJC‑1295 (no DAC) can enhance GH pulse amplitude and stimulate downstream IGF‑1 signaling for anabolic effects.

Clinical and preclinical studies have linked CJC‑1295 (general notes across versions) to increases in GH/IGF‑1, improvements in body composition, sleep, and anti-aging markers—though human data remains limited for No DAC specifically.

Disclaimer: CJC-1295 (No DAC) is a research-only compound and is not approved for medical or therapeutic use. All content is for educational purposes only.

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