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DISCLAIMER: This product is strictly for research use only. It is meant solely for laboratory testing and in vitro studies-not for use in or on humans or animals. All details provided on this site are for educational purposes. This item is not intended to be used as a drug, supplement, or cosmetic, and must not be misrepresented as such.

TB-500

TB-500

TB-500 is a synthetic peptide modeled after a naturally occurring protein in the body called Thymosin Beta-4. It is used in research due to its potential to support healing, reduce inflammation, and improve blood flow.

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All peptides arrive in powdered form for stability.

Third-Party Verified Purity
Third-Party Verified Purity

Each batch is tested and certified to meet or exceed 99% purity standards.

Made in the USA
Made in the USA

Produced in United States WHO/GMP and ISO 9001:2015 certified facilities.

Rigorous Quality Control
Rigorous Quality Control

Double-tested to ensure the highest quality for the most effective research.

What is TB-500?

TB-500 is a synthetic peptide that replicates a portion of Thymosin Beta-4 (Tβ4), a naturally occurring protein found in most human tissues and blood platelets. It is involved in tissue regeneration, cell migration, and immune modulation. Research has focused on TB-500's role in accelerating recovery from muscle, tendon, and ligament injuries, as well as improving cardiovascular and skin repair outcomes.

Potential Benefits Shown in Studies

  • Healing soft tissue like muscles, tendons, and ligaments
  • Promoting blood vessel growth (angiogenesis)
  • Supporting healthy circulation
  • Reducing inflammation and oxidative stress
  • Improving flexibility and recovery in injured tissue
  • Supporting cell migration and tissue repair
  • Enhancing wound healing in skin, eyes, and internal organs

Mechanisms of Action

TB-500's therapeutic potential is largely attributed to:

  • Upregulating actin-binding proteins to support cell structure and migration
  • Promoting angiogenesis (the growth of new blood vessels)
  • Reducing inflammation and oxidative stress at injury sites
  • Stimulating satellite cell differentiation to repair muscle tissue
  • Improving circulation and oxygen delivery to damaged tissues

Molecular Structure of TB-500

TB-500 molecular structure

Sequence

Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser

Molecular Properties

Formula

C₂₁₂H₃₅₀N₅₆O₇₈S

Weight

4963.49 g/mol

Source
PubChem

TB-500 Research Highlights

TB‑500 influences cytoskeletal dynamics by binding to actin monomers (G-actin), promoting cell mobility and facilitating critical steps in tissue repair.

Animal studies demonstrate that TB‑500 accelerates wound healing, encourages blood vessel formation (angiogenesis), and mitigates inflammation, supporting recovery across multiple tissue types.

Clinical studies with native thymosin β‑4 (Tβ4) have shown accelerated healing of pressure ulcers and corneal injuries, indicating translational potential for TB‑500 in human tissue repair.

Disclaimer: TB-500 is classified as a research compound and is not approved for human consumption. This content is intended for educational purposes only.

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