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NAD+ and B12 (Blend)
NAD⁺ and B12 are studied together for their potential to boost energy metabolism, support brain function, and promote cellular repair through complementary roles in mitochondrial and neurological health.
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Each batch is tested and certified to meet or exceed 99% purity standards.
Made in the USA
Produced in United States WHO/GMP and ISO 9001:2015 certified facilities.
Rigorous Quality Control
Double-tested to ensure the highest quality for the most effective research.
What is NAD+ and B12 (Blend)?
NAD⁺ (nicotinamide adenine dinucleotide) is a coenzyme present in all living cells, essential for energy production, mitochondrial function, and cellular repair. It plays a central role in redox reactions, transferring electrons in metabolic pathways, and is required for the activation of sirtuins and other enzymes involved in DNA repair and healthy aging. Vitamin B12 (cobalamin) is an essential water-soluble vitamin involved in red blood cell formation, neurological function, and DNA synthesis. When studied together, NAD⁺ and B12 are explored for their potential synergistic effects on energy metabolism, cognitive support, and cellular health.
Potential Benefits Shown in Studies
- Enhanced Cellular Energy Production
- Improved Mitochondrial Function
- Cognitive Support & Neurological Health
- DNA Repair & Cellular Longevity
- Support for Red Blood Cell Formation & Oxygen Delivery
Mechanisms of Action
NAD⁺ + B12 may work together by:
- NAD⁺: Supporting mitochondrial ATP production through oxidative phosphorylation
- B12: Acting as a cofactor in the conversion of homocysteine to methionine, aiding methylation and DNA synthesis
- Enhancing cellular energy metabolism by improving nutrient utilization pathways
- Supporting neurological function by maintaining myelin sheath integrity and neurotransmitter production
- Protecting against oxidative stress and supporting cellular repair mechanisms
- Promoting healthy aging processes through sirtuin activation (NAD⁺) and DNA stability (B12)
Molecular Structure of Blend Components
Molecular Properties
Chemical Name: Nicotinamide Adenine Dinucleotide (oxidized form)
Structure Features: NAD+ consists of two nucleotides (adenine and nicotinamide) joined through their phosphate groups.
NAD+ and B12 (Blend) Research Highlights
A Harvard-backed clinical study found that overweight adults who supplemented with NMN (a precursor to NAD⁺) for 28 days experienced:
- Significant weight loss
- Lower cholesterol levels
- Reduced blood pressure
These results suggest NAD⁺-boosting compounds may help manage weight and cardiometabolic risk in aging populations.
Research indicates that NAD⁺ precursors like NMN may improve how the body responds to insulin, reducing the risk of type 2 diabetes and improving glucose control.
NAD⁺ plays a role in maintaining brain function. It supports mitochondrial energy in brain cells and protects neurons against damage:
- Potential benefits in age-related cognitive decline
- Early evidence for use in Alzheimer's and Parkinson's models
- Improves cellular energy availability in the brain
NAD⁺ fuels mitochondrial enzymes that regulate aging and stress responses. Restoring NAD⁺ levels is associated with:
- Slower biological aging markers
- Enhanced cellular resilience
- Better skin quality and energy output
Studies show NAD⁺ may help reduce systolic blood pressure and improve endothelial function, supporting heart and vessel health.